ST. LOUIS COUNTY, Mo. — A crash involving two commercial vehicles killed one person and critically injured two others early Thursday, Nov. 5, 2026, on Interstate 270 in south St. Louis County, closing all northbound lanes.

The crash occurred shortly before 4 a.m. on northbound I-270 past Tesson Ferry Road, according to the Missouri Department of Transportation. The cause of the accident was not yet provided by the Missouri State Highway Patrol.

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Northbound lanes are expected to remain closed throughout the morning commute, according to the Missouri State Highway Patrol. Officials are working to divert traffic to South Lindbergh or Missouri 141.

Two southbound lanes of I-270 remain open, officials said.

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